Disperse Systems to be continued...

DISPERSE SYSTEMS
SUSPENSION -          Finely divided particles distribute somewhat uniformly  throughouta vehicle in which the drug exhibits a minimum degree of solubility -          GOOD SUSPENSION: particle diameter: 1 to 50 micrometer -          MICROPULVERIZATION;Producing fine powders: 10 to 50 micrometer -          FLUID ENERGY/JET MILLING/ MICRONIZING--Under 10 um      ……Floc/floccules- intentional formation of loose aggregates of particles, forming type of lattice that resist complete settling. It breaks up easily with small amount of agitation
EMULSIONS -          Dispersion in which the dispersed phase is composed of small globules of a liquid distributed throughout a vehicle in which it is immiscible
Theories of Emulsification
1.       Surface tension theory
2.       Oriented wedge theory	Assumes mono-molecular layers of emulsifying agent curved around the droplet of the internal phase of the emulsion
3.       Interfacial film theory	Places the emulsifying agent  at the interface between theoil and water, surrounding the droplets of the internal phase as a thin layer of film adsorbed on the surface of the drops